özofagus varis kanamalarında
250 mcg puşe 1 dakikada ve ardından saatte 250 mcg infüzyon 5 gün önerilir. SF veya %5 dextrose içinde verilebilir. bu sürede ışıktan korunmalıdır.
To treat upper GI (gastrointestinal) hemorrhage: The
initial dose should be 250 mcg slow IV (over 1 min),
and then immediately followed by a continuous
infusion of 3 mg/12 hr (6 mg/24 hr) for 5 days.
The 3 mg lyophilized powder for continuous infusion should be
reconstituted in either sterile normal (0.9%) saline or in 5% dextrose
to provide sufficient solution for a 12-hour infusion of somatostatin at
a rate of 250 µg/hr (approximately 3.5 µg/kg/hr). Once reconstituted it
should be used within 24 hours and should be protected from light
during this time.
To treat acute pancreatitis: Same as for GI bleeding except that it may be infused for 44 hours.
To treat enterocutaneous fistulas: Continuous
infusions of 6 mg/24 hr (3 mg/12 hr), and the
treatment should be maintained until complete closure
of the fistula. The dose should then be reduced to
50 % over 48 hour period to avoid any rebound effect. 
